Prediction of the Blood-Brain Barrier Permeability Using RP-18 Thin Layer Chromatography

Prediction of the Blood-Brain Barrier Permeability Using RP-18 Thin Layer Chromatography

The Blood-Brain Barrier (BBB) permeability is an important factor governing a drug’s ability to act upon the Central Nervous System. The measure of the BBB permeability used throughout this study is the log BB (the blood/brain partitioning coefficient) measured in vivo or calculated. Useful yet simp...

Full description

Bibliographic Details
Main Authors: Sobańska Anna W., Wanat Karolina, Brzezińska Elżbieta
Format: Article
Language:English
Published: De Gruyter 2019-02-01
Series:Open Chemistry
Subjects:
rp-18 tlc
qsar
blood-brain barrier
chemometric techniques
Online Access:https://doi.org/10.1515/chem-2019-0005

Similar Items

Similar Items