Intracranial aneurysm’s association with genetic variants, transcription abnormality, and methylation changes in ADAMTS genes

Intracranial aneurysm’s association with genetic variants, transcription abnormality, and methylation changes in ADAMTS genes

Purpose The development of intracranial aneurysm (IA) has been linked to genetic factors. The current study examines the potential role of genes encoding disintegrin and metalloproteinase using thrombospondin motifs (ADAMTS) in IA development. Material and Methods High-throughput whole-genome and wh...

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Bibliographic Details
Main Authors: Shi Chen, Mengqi Li, Wenqiang Xin, Shengze Liu, Linfei Zheng, Yan Li, Mengyao Li, Mengxiong Zhan, Xinyu Yang
Format: Article
Language:English
Published: PeerJ Inc. 2020-02-01
Series:PeerJ
Subjects:
ADMTSL1
Bioinformatics
Hemorrhagic stroke
Single-nucleotide variants
Online Access:https://peerj.com/articles/8596.pdf

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