A hSCARB2-transgenic mouse model for Coxsackievirus A16 pathogenesis

Abstract Background Coxsackievirus A16 (CA16) is one of the neurotropic pathogen that has been associated with severe neurological forms of hand, foot, and mouth disease (HFMD), but its pathogenesis is not yet clear. The limited host range of CA16 make the establishment of a suitable animal model th...

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Bibliographic Details
Main Authors: Yanli Chen, Heng Li, Jinxi Yang, Huiwen Zheng, Lei Guo, Weiyu Li, Zening Yang, Jie Song, Longding Liu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-021-01557-5