Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine

Hippocampus Metabolic Disturbance and Autophagy Deficiency in Olfactory Bulbectomized Rats and the Modulatory Effect of Fluoxetine

An olfactory bulbectomy (OBX) rodent is a widely-used model for depression (especially for agitated depression). The present study aims to investigate the hippocampus metabolic profile and autophagy-related pathways in OBX rats and to explore the modulatory roles of fluoxetine. OBX rats were given a...

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Bibliographic Details
Main Authors: Yunfeng Zhou, Xue Tao, Zhi Wang, Li Feng, Lisha Wang, Xinmin Liu, Ruile Pan, Yonghong Liao, Qi Chang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
olfactory bulbectomy
depression
hippocampus
metabonomics
autophagy
Online Access:https://www.mdpi.com/1422-0067/20/17/4282

Internet

https://www.mdpi.com/1422-0067/20/17/4282

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