Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction

Tissue Renin-Angiotensin System (tRAS) Induce Intervertebral Disc Degeneration by Activating Oxidative Stress and Inflammatory Reaction

Lumbar intervertebral disc degeneration (IDD) has been the major contributor to low back pain (LBP). IDD is an chronic inflammation process, with the activation of plentiful inflammation-related cytokines and ECM degradation-related enzymes. In the past few years, hypertension has been reported to c...

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Bibliographic Details
Main Authors: Kaiqiang Sun, Xiaofei Sun, Jingchuan Sun, Yan Jiang, Feng Lin, Fanqi Kong, Fudong Li, Jian Zhu, Le Huan, Bing Zheng, Yuan Wang, Weiguo Zou, Lu Gao, Ximing Xu, Jiangang Shi
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/3225439

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