Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγ.

Anticancer activities of pterostilbene-isothiocyanate conjugate in breast cancer cells: involvement of PPARγ.

Trans-3,5-dimethoxy-4'-hydroxystilbene (PTER), a natural dimethylated analog of resveratrol, preferentially induces certain cancer cells to undergo apoptosis and could thus have a role in cancer chemoprevention. Peroxisome proliferator-activated receptor γ (PPARγ), a member of the nuclear recep...

Full description

Bibliographic Details
Main Authors:	Kumar Nikhil, Shruti Sharan, Abhimanyu K Singh, Ajanta Chakraborty, Partha Roy
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25119466/?tool=EBI

Similar Items

Pterostilbene-isothiocyanate conjugate suppresses growth of prostate cancer cells irrespective of androgen receptor status.
by: Kumar Nikhil, et al.
Published: (2014-01-01)

Anticancer activity of sulforaphane and allyl isothiocyanate-conjugated silicon quantum dots
by: Liu, Peng
Published: (2017)

Protective effects of pterostilbene on ulcerative colitis in rats via suppressing NF-κB pathway and activating PPAR-γ
by: Liu Shi, et al.
Published: (2019-03-01)

Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization
by: Kai-Wei Tang, et al.
Published: (2021-08-01)

Identification of an irreversible PPARγ antagonist with potent anticancer activity
by: Youyi Peng, et al.
Published: (2020-12-01)

Allyl Isothiocyanate Exhibits No Anticancer Activity in MDA-MB-231 Breast Cancer Cells
by: Md. Abu Sayeed, et al.
Published: (2018-01-01)

Resveratrol and Pterostilbene Exhibit Anticancer Properties Involving the Downregulation of HPV Oncoprotein E6 in Cervical Cancer Cells
by: Kaushiki Chatterjee, et al.
Published: (2018-02-01)

The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms
by: Jessica R. Miller, et al.
Published: (2008-03-01)

PPARs and Anticancer Therapies
by: Michael E. C. Robbins, et al.
Published: (2010-01-01)

Anticancer Role of PPARγ Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes
by: P. J. Simpson-Haidaris, et al.
Published: (2010-01-01)

The Anticancer Properties of Phenethyl Isothiocyanate for Human Brain Glioblastoma Cells
by: Yu-Cheng Chou, et al.
Published: (2015)

Synergistic Antiproliferative Effects of Combined γ-Tocotrienol and PPARγ Antagonist Treatment Are Mediated through PPARγ-Independent Mechanisms in Breast Cancer Cells
by: Abhita Malaviya, et al.
Published: (2014-01-01)

The Effects of Conjugated Linoleic Acid and PPARγInducer on the Regulation of Antioxidant System in Mice
by: Chien-I Lee, et al.
Published: (2011)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
by: Ajit A. Kulkarni, et al.
Published: (2012-01-01)

Comparative studies on anti-avian sera conjugated with fluorescin isothiocyanate
by: M. H. Khodeir, et al.
Published: (2010-12-01)

Determination of Isothiocyanate-Protein Conjugates in a Vegetable-Enriched Bread
by: Mareike Krell, et al.
Published: (2021-06-01)

Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes.
by: Shan Jiang, et al.
Published: (2012-01-01)

Pterostilbene caffeine co-crystal: Bioavailable caffeine alternative enriched with pterostilbene
by: Roopesh Jain
Published: (2020-01-01)

New Mild and Simple Approach to Isothiocyanates: A Class of Potent Anticancer Agents
by: Bingling Luo, et al.
Published: (2017-06-01)

Designing of the Anticancer Nanocomposite with Sustained Release Properties by Using Graphene Oxide Nanocarrier with Phenethyl Isothiocyanate as Anticancer Agent
by: Dasan Mary Jaya Seema, et al.
Published: (2018-08-01)

PPARγ, neuroinflammation, and disease
by: Mrak Robert E, et al.
Published: (2004-05-01)

PPAR-γ in the Cardiovascular System
by: Sheng Zhong Duan, et al.
Published: (2008-01-01)

Nutraceuticals as Ligands of PPARγ
by: Meera Penumetcha, et al.
Published: (2012-01-01)

PPARγ and Cognitive Performance
by: Michele d’Angelo, et al.
Published: (2019-10-01)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex.
by: Justin A Lemkul, et al.
Published: (2015-01-01)

Estrogen receptor-α36 is involved in pterostilbene-induced apoptosis and anti-proliferation in in vitro and in vivo breast cancer.
by: Chi Pan, et al.
Published: (2014-01-01)

Pterostilbene in Cancer Therapy
by: Elena Obrador, et al.
Published: (2021-03-01)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
by: Robert I. Glazer, et al.
Published: (2008-01-01)

Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes.
by: Alexandra Rogue, et al.
Published: (2011-01-01)

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
by: Paterniti Irene, et al.
Published: (2013-02-01)

Scaffold-based pan-agonist design for the PPARα, PPARβ and PPARγ receptors.
by: Li-Song Zhang, et al.
Published: (2012-01-01)

GW9662, an antagonist of PPAR-gamma, inhibits breast tumour cell growth and promotes the anticancer effects of the PPAR-gamma agonist Rosiglitazone, independently of PPAR-gamma activation.
by: Gill, Jason H., et al.
Published: (2009)

PPARα and PPARγ as main regulators of fatty acid metabolism
by: Mirosław Kucharski, et al.
Published: (2018-10-01)

PPARγ in Inflammatory Bowel Disease
by: Vito Annese, et al.
Published: (2012-01-01)

Effects of PPARγ Ligands on Leukemia
by: Yoko Tabe, et al.
Published: (2012-01-01)

Prostaglandins as PPARγ Modulators in Adipogenesis
by: Ko Fujimori
Published: (2012-01-01)

PPARγ et homéostasie intestinale
by: Fumery, Mathurin
Published: (2018)

Pterostilbene exerts anticancer activity on non-small-cell lung cancer via activating endoplasmic reticulum stress
by: Zhiqiang Ma, et al.
Published: (2017-08-01)

Oxaliplatin neurotoxicity involves peroxisome alterations. PPARγ agonism as preventive pharmacological approach.
by: Matteo Zanardelli, et al.
Published: (2014-01-01)

Involvement of PPARγ in the Anticonvulsant Activity of EP-80317, a Ghrelin Receptor Antagonist
by: Chiara Lucchi, et al.
Published: (2017-09-01)