Telomere Length Shortening in Microglia: Implication for Accelerated Senescence and Neurocognitive Deficits in HIV

Telomere Length Shortening in Microglia: Implication for Accelerated Senescence and Neurocognitive Deficits in HIV

The widespread use of combination antiretroviral therapy (cART) has led to the accelerated aging of the HIV-infected population, and these patients continue to have a range of mild to moderate HIV-associated neurocognitive disorders (HAND). Infection results in altered mitochondrial function. The HI...

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Bibliographic Details
Main Authors: Chiu-Bin Hsiao, Harneet Bedi, Raquel Gomez, Ayesha Khan, Taylor Meciszewski, Ravikumar Aalinkeel, Ting Chean Khoo, Anna V. Sharikova, Alexander Khmaladze, Supriya D. Mahajan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Vaccines
Subjects:
HIV-associated neurocognitive disorders (HAND)
telomere length
telomerase
microglia
neuro-inflammation
oxidative stress
Online Access:https://www.mdpi.com/2076-393X/9/7/721

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https://www.mdpi.com/2076-393X/9/7/721

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