Therapeutic Potential of MicroRNA Let-7: Tumor Suppression or Impeding Normal Stemness

The first microRNA, let-7, and its family were discovered in Caenorhabditis elegans and are functionally conserved from worms to humans in the regulation of embryonic development and stemness. The let-7 family has been shown to have an essential role in stem cell differentiation and tumor-suppressiv...

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Main Authors: Shao-Chih Chiu, Hao-Yu Chung, Der-Yang Cho, Tzu-Min Chan, Ming-Chao Liu, Hiang-Ming Huang, Tsyng-You Li, Jian-Yong Lin, Pei-Chang Chou, Ru-Huei Fu, Wen-Kuang Yang, Horng-Jyh Harn, Shinn-Zong Lin M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2014-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368914X678418