Recombinant protein expression by targeting pre-selected chromosomal loci

Recombinant protein expression by targeting pre-selected chromosomal loci

<p>Abstract</p> <p>Background</p> <p>Recombinant protein expression in mammalian cells is mostly achieved by stable integration of transgenes into the chromosomal DNA of established cell lines. The chromosomal surroundings have strong influences on the expression of tra...

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Bibliographic Details
Main Authors:	Krömer Wolfgang, da Gama-Norton Leonor, Schucht Roland, Nehlsen Kristina, Baer Alexandra, Cayli Aziz, Hauser Hansjörg, Wirth Dagmar
Format:	Article
Language:	English
Published:	BMC 2009-12-01
Series:	BMC Biotechnology
Online Access:	http://www.biomedcentral.com/1472-6750/9/100

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