Crystal structure of pirfenidone (5-methyl-1-phenyl-1H-pyridin-2-one): an active pharmaceutical ingredient (API)

Crystal structure of pirfenidone (5-methyl-1-phenyl-1H-pyridin-2-one): an active pharmaceutical ingredient (API)

The crystal structure of pirfenidone, C12H11NO [alternative name: 5-methyl-1-phenylpyridin-2(1H)-one], an active pharmaceutical ingredient (API) approved in Europe and Japan for the treatment of Idiopathic pulmonary fibrosis (IPF), is reported here for the first time. It was crystallized from toluen...

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Bibliographic Details
Main Authors: Mauro Barbero, Matteo Mossotti, Angelo Sironi, Giovanni Battista Giovenzana, Valentina Colombo
Format: Article
Language:English
Published: International Union of Crystallography 2019-07-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
pirfenidone
active pharmaceutical ingredient (API)
idiopathic pulmonary fibrosis (IPF)
hydrogen bonding
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989019006418

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