Identification and Quantification of Bioactive Molecules Inhibiting Pro-inflammatory Cytokine Production in Spent Coffee Grounds Using Metabolomics Analyses

Identification and Quantification of Bioactive Molecules Inhibiting Pro-inflammatory Cytokine Production in Spent Coffee Grounds Using Metabolomics Analyses

In this study, we assessed the anti-inflammatory properties of spent coffee grounds. Methanolic extracts of spent coffee grounds obtained from 3 Arabica cultivars possess compounds that exerted inhibitory effects on the secretion of inflammatory mediators (TNF-α, IL-6, and IL-10) induced by a human...

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Bibliographic Details
Main Authors: Khanh-Van Ho, Kathy L. Schreiber, Jihyun Park, Phuc H. Vo, Zhentian Lei, Lloyd W. Sumner, Charles R. Brown, Chung-Ho Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
untargeted analysis
metabolomics
phenolics
anti-inflammatory
spent coffee grounds
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00229/full

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