Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer

Molecular Characterization of Non-responders to Chemotherapy in Serous Ovarian Cancer

Nearly one-third of patients with high-grade serous ovarian cancer (HGSC) do not respond to initial treatment with platinum-based therapy. Genomic and clinical characterization of these patients may lead to potential alternative therapies. Here, the objective is to classify non-responders into subse...

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Bibliographic Details
Main Authors: Megan E. McDonald, Erin A. Salinas, Eric J. Devor, Andreea M. Newtson, Kristina W. Thiel, Michael J. Goodheart, David P. Bender, Brian J. Smith, Kimberly K. Leslie, Jesus Gonzalez-Bosquet
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
serous ovarian cancer
chemotherapy response
TCGA
iCLusterPlus
Unsupervised clustering
Online Access:http://www.mdpi.com/1422-0067/20/5/1175

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