Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage

Dengue Virus Infection Activates Interleukin-1β to Induce Tissue Injury and Vascular Leakage

Dengue virus (DENV) infection causes several diseases ranging from dengue fever to life-threatening dengue hemorrhagic fever and dengue shock syndrome characterized by endothelial dysfunction, vascular leakage, and shock. Here, we identify a potential mechanism by which DENV induces tissue injury an...

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Bibliographic Details
Main Authors: Pan Pan, Qi Zhang, Weiyong Liu, Wenbiao Wang, Zhenyang Yu, Zizhao Lao, Wei Zhang, Miaomiao Shen, Pin Wan, Feng Xiao, Muhammad Adnan Shereen, Wen Zhang, Qiuping Tan, Yuntao Liu, Xiaohong Liu, Kailang Wu, Yingle Liu, Geng Li, Jianguo Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
dengue virus
inflammatory response
IL-1RA
IL-1β
NLRP3 inflammasome
vascular leakage
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02637/full

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