Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region

Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region

Different human papillomavirus (HPV) types are characterized by differences in tissue tropism and ability to promote cell proliferation and transformation. In addition, clinical and experimental studies have shown that some genetic variants/lineages of high-risk HPV (HR-HPV) types are characterized...

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Bibliographic Details
Main Authors: Enrico Lavezzo, Giulia Masi, Stefano Toppo, Elisa Franchin, Valentina Gazzola, Alessandro Sinigaglia, Serena Masiero, Marta Trevisan, Silvana Pagni, Giorgio Palù, Luisa Barzon
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Viruses
Subjects:
human papillomavirus
genotyping
next-generation sequencing
E6/E7
subtype
variant
cervical cancer
high-risk HPV
deep sequencing
pyrosequencing
Online Access:http://www.mdpi.com/1999-4915/8/3/79

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