Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

Abstract Background Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to PfEMP1 antigens may contribute to na...

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Bibliographic Details
Main Authors: Emily M. Stucke, Amadou Niangaly, Andrea A. Berry, Jason A. Bailey, Drissa Coulibaly, Amed Ouattara, Kirsten E. Lyke, Matthew B. Laurens, Antoine Dara, Matthew Adams, Jozelyn Pablo, Algis Jasinskas, Rie Nakajima, Albert E. Zhou, Sonia Agrawal, DeAnna J. Friedman-Klabanoff, Shannon Takala-Harrison, Bourema Kouriba, Abdoulaye K. Kone, J. Alexandra Rowe, Ogobara K. Doumbo, Philip L. Felgner, Mahamadou A. Thera, Christopher V. Plowe, Mark A. Travassos
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Malaria Journal
Subjects:
Malaria
Plasmodium falciparum
var genes
PfEMP1
Immunity
Seroreactivity
Online Access:http://link.springer.com/article/10.1186/s12936-019-2905-9

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