Reconstructing cancer genomes from paired-end sequencing data

<p>Abstract</p> <p>Background</p> <p>A cancer genome is derived from the germline genome through a series of somatic mutations. Somatic structural variants - including duplications, deletions, inversions, translocations, and other rearrangements - result in a cancer gen...

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Bibliographic Details
Main Authors: Oesper Layla, Ritz Anna, Aerni Sarah J, Drebin Ryan, Raphael Benjamin J
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Bioinformatics