Aromatic Thioacetal-Bridged ROS-Responsive Nanoparticles as Novel Gene Delivery Vehicles

In this report, a series of polycations are designed and synthesized by conjugating reactive oxygen species (ROS)-responsive thioacetal-linkers to low molecular weight (LMW) polyethylenimine (PEI) via ring-opening polymerization. Their structure–activity relationships (SARs) as gene delive...

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Bibliographic Details
Main Authors: Guo-Qing Lin, Wen-Jing Yi, Qiang Liu, Xue-Jun Yang, Zhi-Gang Zhao
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/8/2061