Efficacy of osimertinib for preventing leptomeningeal metastasis derived from advanced EGFR-mutated non-small cell lung cancer: a propensity-matched retrospective study

Efficacy of osimertinib for preventing leptomeningeal metastasis derived from advanced EGFR-mutated non-small cell lung cancer: a propensity-matched retrospective study

Abstract Background Leptomeningeal metastasis (LM) is a severe complication of advanced non-small cell lung cancer (NSCLC). This retrospective study aimed to investigate the potential use of osimertinib for preventing LM in patients with advanced epidermal growth factor receptor (EGFR)-mutated NSCLC...

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Bibliographic Details
Main Authors:	Xia Wang, Jing Cai, Zhimin Zeng, Anwen Liu
Format:	Article
Language:	English
Published:	BMC 2021-07-01
Series:	BMC Cancer
Subjects:	Non-small-cell lung cancer Epidermal growth factor receptor Tyrosine kinase inhibitors Leptomeningeal metastasis Osimertinib Propensity score matching
Online Access:	https://doi.org/10.1186/s12885-021-08581-2

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