Morphology regulation in vascular endothelial cells

Abstract Morphological change in endothelial cells is an initial and crucial step in the process of establishing a functional vascular network. Following or associated with differentiation and proliferation, endothelial cells elongate and assemble into linear cord-like vessels, subsequently forming...

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Main Authors:	Kiyomi Tsuji-Tamura, Minetaro Ogawa
Format:	Article
Language:	English
Published:	BMC 2018-09-01
Series:	Inflammation and Regeneration
Subjects:	Vasculature Endothelial cells Angiogenesis Morphology Elongation
Online Access:	http://link.springer.com/article/10.1186/s41232-018-0083-8

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spelling	doaj-2bb7baf9b05449a38f31fa6f5ae162422020-11-24T21:35:12ZengBMCInflammation and Regeneration1880-81902018-09-0138111310.1186/s41232-018-0083-8Morphology regulation in vascular endothelial cellsKiyomi Tsuji-Tamura0Minetaro Ogawa1Department of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto UniversityDepartment of Cell Differentiation, Institute of Molecular Embryology and Genetics, Kumamoto UniversityAbstract Morphological change in endothelial cells is an initial and crucial step in the process of establishing a functional vascular network. Following or associated with differentiation and proliferation, endothelial cells elongate and assemble into linear cord-like vessels, subsequently forming a perfusable vascular tube. In vivo and in vitro studies have begun to outline the underlying genetic and signaling mechanisms behind endothelial cell morphology regulation. This review focuses on the transcription factors and signaling pathways regulating endothelial cell behavior, involved in morphology, during vascular development.http://link.springer.com/article/10.1186/s41232-018-0083-8VasculatureEndothelial cellsAngiogenesisMorphologyElongation
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kiyomi Tsuji-Tamura Minetaro Ogawa
spellingShingle	Kiyomi Tsuji-Tamura Minetaro Ogawa Morphology regulation in vascular endothelial cells Inflammation and Regeneration Vasculature Endothelial cells Angiogenesis Morphology Elongation
author_facet	Kiyomi Tsuji-Tamura Minetaro Ogawa
author_sort	Kiyomi Tsuji-Tamura
title	Morphology regulation in vascular endothelial cells
title_short	Morphology regulation in vascular endothelial cells
title_full	Morphology regulation in vascular endothelial cells
title_fullStr	Morphology regulation in vascular endothelial cells
title_full_unstemmed	Morphology regulation in vascular endothelial cells
title_sort	morphology regulation in vascular endothelial cells
publisher	BMC
series	Inflammation and Regeneration
issn	1880-8190
publishDate	2018-09-01
description	Abstract Morphological change in endothelial cells is an initial and crucial step in the process of establishing a functional vascular network. Following or associated with differentiation and proliferation, endothelial cells elongate and assemble into linear cord-like vessels, subsequently forming a perfusable vascular tube. In vivo and in vitro studies have begun to outline the underlying genetic and signaling mechanisms behind endothelial cell morphology regulation. This review focuses on the transcription factors and signaling pathways regulating endothelial cell behavior, involved in morphology, during vascular development.
topic	Vasculature Endothelial cells Angiogenesis Morphology Elongation
url	http://link.springer.com/article/10.1186/s41232-018-0083-8
work_keys_str_mv	AT kiyomitsujitamura morphologyregulationinvascularendothelialcells AT minetaroogawa morphologyregulationinvascularendothelialcells
_version_	1725946116513464320

Morphology regulation in vascular endothelial cells

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