Long-Term Impact of Cyclosporin Reduction with MMF Treatment in Chronic Allograft Dysfunction: REFERENECE Study 3-Year Follow Up

Calcineurin inhibitor (CNI) toxicity contributes to chronic allograft nephropathy (CAN). In the 2-year, randomized, study, we showed that 50% cyclosporin (CsA) reduction in combination with mycophenolate mofetil (MMF) treatment improves kidney function without increasing the risk for graft rejection...

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Bibliographic Details
Main Authors: L. Frimat, E. Cassuto-Viguier, F. Provôt, L. Rostaing, B. Charpentier, K. Akposso, M. C. Moal, P. Lang, D. Glotz, S. Caillard, D. Ducloux, C. Pouteil-Noble, S. Girardot-Seguin, M. Kessler
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2010/402750