Azithromycin Exhibits Activity Against Pseudomonas aeruginosa in Chronic Rat Lung Infection Model

Azithromycin Exhibits Activity Against Pseudomonas aeruginosa in Chronic Rat Lung Infection Model

Pseudomonas aeruginosa forms biofilms in the lungs of chronically infected cystic fibrosis patients, which are tolerant to both the treatment of antibiotics and the host immune system. Normally, antibiotics are less effective against bacteria growing in biofilms; azithromycin has shown a potent effi...

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Bibliographic Details
Main Authors: Manoj Kumar, Madhvi Rao, Tarun Mathur, Tarani Kanta Barman, Vattan Joshi, Tridib Chaira, Smita Singhal, Manisha Pandya, Souhaila Al Khodor, Dilip J. Upadhyay, Nobuhisa Masuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
Gram-negative bacteria
PA-14
PAO1
multidrug resistance
respiratory tract infection
pel genes
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.603151/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.603151/full

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