Inducible Expression of spo0A as a Universal Tool for Studying Sporulation in Clostridium difficile

Inducible Expression of spo0A as a Universal Tool for Studying Sporulation in Clostridium difficile

Clostridium difficile remains a leading nosocomial pathogen, putting considerable strain on the healthcare system. The ability to form endospores, highly resistant to environmental insults, is key to its persistence and transmission. However, important differences exist between the sporulation pathw...

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Bibliographic Details
Main Authors: Marcin Dembek, Stephanie E. Willing, Huynh A. Hong, Siamand Hosseini, Paula S. Salgado, Simon M. Cutting
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
sporulation
Clostridium difficile
spo0A
spore
inducible expression
allele-coupled exchange
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01793/full

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