Expanding the Toolbox of E3 Ligases for Protein Degradation: Targeting the “Undruggable” Fbw7 E3 Ligase
Proteolysis targeting chimera molecules (PROTACS) are heterobifunctional small molecules<br />designed to induce intracellular protein degradation [...]
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-11-01
|
Series: | Proceedings |
Subjects: | |
Online Access: | https://www.mdpi.com/2504-3900/22/1/101 |