Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells

Fast-spiking parvalbumin-expressing interneurons (PVIs) and granule cells of the dentate gyrus receive layer-specific dendritic inhibition. The authors show that distal and proximal dendritic inhibition differentially control input-output transformations in PVIs and granule cells.

Bibliographic Details
Main Authors: Claudio Elgueta, Marlene Bartos
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13533-3
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spelling doaj-2b96fbf04206410ba939e593541038412021-05-11T12:10:44ZengNature Publishing GroupNature Communications2041-17232019-12-0110111510.1038/s41467-019-13533-3Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cellsClaudio Elgueta0Marlene Bartos1Institute for Physiology I, Cellular and Systemic Neurophysiology, Medical Faculty of the University of FreiburgInstitute for Physiology I, Cellular and Systemic Neurophysiology, Medical Faculty of the University of FreiburgFast-spiking parvalbumin-expressing interneurons (PVIs) and granule cells of the dentate gyrus receive layer-specific dendritic inhibition. The authors show that distal and proximal dendritic inhibition differentially control input-output transformations in PVIs and granule cells.https://doi.org/10.1038/s41467-019-13533-3
collection DOAJ
language English
format Article
sources DOAJ
author Claudio Elgueta
Marlene Bartos
spellingShingle Claudio Elgueta
Marlene Bartos
Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
Nature Communications
author_facet Claudio Elgueta
Marlene Bartos
author_sort Claudio Elgueta
title Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
title_short Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
title_full Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
title_fullStr Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
title_full_unstemmed Dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
title_sort dendritic inhibition differentially regulates excitability of dentate gyrus parvalbumin-expressing interneurons and granule cells
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-12-01
description Fast-spiking parvalbumin-expressing interneurons (PVIs) and granule cells of the dentate gyrus receive layer-specific dendritic inhibition. The authors show that distal and proximal dendritic inhibition differentially control input-output transformations in PVIs and granule cells.
url https://doi.org/10.1038/s41467-019-13533-3
work_keys_str_mv AT claudioelgueta dendriticinhibitiondifferentiallyregulatesexcitabilityofdentategyrusparvalbuminexpressinginterneuronsandgranulecells
AT marlenebartos dendriticinhibitiondifferentiallyregulatesexcitabilityofdentategyrusparvalbuminexpressinginterneuronsandgranulecells
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