T Follicular Helper Cells in Autoimmune Disorders

T Follicular Helper Cells in Autoimmune Disorders

T follicular helper (Tfh) cells are a distinct subset of CD4+ T lymphocytes, specialized in B cell help and in regulation of antibody responses. They are required for the generation of germinal center reactions, where selection of high affinity antibody producing B cells and development of memory B...

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Bibliographic Details
Main Authors: Noémie Gensous, Manon Charrier, Dorothée Duluc, Cécile Contin-Bordes, Marie-Elise Truchetet, Estibaliz Lazaro, Pierre Duffau, Patrick Blanco, Christophe Richez
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
auto-immunity
auto-immune diseases
T cells
T helper follicular cells
systemic lupus erythematosus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01637/full

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