Effects of TLR3 and TLR9 Signaling Pathway on Brain Protection in Rats Undergoing Sevoflurane Pretreatment during Cardiopulmonary Bypass

Effects of TLR3 and TLR9 Signaling Pathway on Brain Protection in Rats Undergoing Sevoflurane Pretreatment during Cardiopulmonary Bypass

Objective. To investigate the effects of TLR3 and TLR9 signaling pathway on brain injury during CPB in rats pretreated with sevoflurane and its possible molecular mechanism. Methods. SD rats were randomly assigned to sham group, CPB group, and Sev group. Brain tissue was obtained at before CPB (T0),...

Full description

Bibliographic Details
Main Authors:	Zhou Nan, Zhou Jin, Cao Huijuan, Zhang Tiezheng, Chen Keyan
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2017/4286738

Similar Items

TLR2 AND TLR4 EXPRESSION ON BLOOD MONOCYTES AND GRANULOCYTES OF CARDIAC SURGICAL PATIENTS IS NOT AFFECTED BY THE USE OF CARDIOPULMONARY BYPASS
by: Jan Krejsek, et al.
Published: (2013-01-01)

Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway
by: Chun Yang, et al.
Published: (2020-01-01)

Sevoflurane inhibits cardiac function in pulmonary fibrosis mice through the TLR4 signaling pathway
by: Yanan Cao, et al.
Published: (2018-09-01)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
by: Mohsin H. K. Roshan, et al.
Published: (2016-01-01)

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
by: del Casar José M, et al.
Published: (2010-12-01)

TLR8, TLR9 and Gfi-1 restrain TLR7-mediated lupus
by: Rodrigues barreto de macedo, Amanda beatriz
Published: (2014)

TLR4 and TLR9 Expression in Different Phenotypes of Rhinitis
by: Maria Lauriello, et al.
Published: (2012-01-01)

Increased expression of TLR7 and TLR9 in alopecia areata
by: Kang, H., et al.
Published: (2019)

Basophil activation through TLR2 and TLR4 signaling pathways
by: Manal Alkan, et al.
Published: (2018-08-01)

TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery.
by: Orna Avlas, et al.
Published: (2015-01-01)

Microglia Induce Neurotoxic IL-17+ γδ T Cells Dependent on TLR2, TLR4, and TLR9 Activation.
by: Katja Derkow, et al.
Published: (2015-01-01)

Association of TLR4 and TLR9 gene polymorphisms and haplotypes with cervicitis susceptibility.
by: Alex Chauhan, et al.
Published: (2019-01-01)

Comparison of human B cell activation by TLR7 and TLR9 agonists
by: Neys Lori, et al.
Published: (2008-07-01)

Synergistic TLR2/6 and TLR9 activation protects mice against lethal influenza pneumonia.
by: Michael J Tuvim, et al.
Published: (2012-01-01)

Analysis of TLR2, TLR4, and TLR9 single nucleotide polymorphisms in children with bacterial meningitis and their healthy family members
by: Ewelina Gowin, et al.
Published: (2017-07-01)

TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion
by: Ying Wang, et al.
Published: (2013-01-01)

Toll-Like Receptor Ligand-Induced Liver Injury in D-Galactosamine-Sensitized Mice: Differences between TLR7/8 and TLR9 Ligands, Cytokine Patterns, and Cross-Tolerance Induction by TLR2 Ligand Pretreatment
by: Reiko Seki
Published: (2017-01-01)

A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria
by: Gunanidhi Dhangadamajhi, et al.

Genetic variation of <it>TLR-4</it>, <it>TLR-9 </it>and <it>TIRAP </it>genes in Iranian malaria patients
by: Mehrizi Akram A, et al.
Published: (2011-04-01)

Expression of TLR2, TLR3, TLR4, and TLR7 on pulmonary lymphocytes of -infected C57BL/6 mice
by: Dianhui Chen, et al.
Published: (2019-05-01)

The role of TLR9 in ocular angiogenesis
by: Wu, Jia-Hui
Published: (2016)

Activation of eosinophils via Toll-like receptor (TLR)3, TLR7 and TLR9: link between viral infection and asthma?
by: Anne Månsson, et al.
Published: (2008-04-01)

The Association of TLR2, TLR3, and TLR9 Gene Polymorphisms With Susceptibility to Talaromycosis Among Han Chinese AIDS Patients in Guangdong
by: Min Wang, et al.
Published: (2021-03-01)

IMPACT OF ANESTHESIA WITH PROLONGED USE OF DESFLURANE AND SEVOFLURANE ON THE CARDIAC FUNCTION IN CORONARY ARTERY BYPASS GRAFT SURGERIES WITH CARDIOPULMONARY BYPASS
by: N. S. Molchan, et al.
Published: (2018-01-01)

Xuezhikang improves the outcomes of cardiopulmonary resuscitation in rats by suppressing the inflammation response through TLR4/NF-κB pathway
by: Licai Liang, et al.
Published: (2019-06-01)

Combined TLR7/8 and TLR9 ligands potentiate the activity of a Schistosoma japonicum DNA vaccine.
by: Xuefeng Wang, et al.
Published: (2013-01-01)

Effect of sevoflurane and propofol on cerebral oxygen metabolism in cardiopulmonary bypass and postoperative neurological function injury
by: Zhu Zhu, et al.
Published: (2016-12-01)

Acquisition of adult-like TLR4 and TLR9 responses during the first year of life.
by: Muriel Nguyen, et al.
Published: (2010-01-01)

Harmful Roles of TLR3 and TLR9 in Cardiac Dysfunction Developing during Polymicrobial Sepsis
by: Fatemeh Fattahi, et al.
Published: (2018-01-01)

TLR3 and TLR9 agonists improve postexposure vaccination efficacy of live smallpox vaccines.
by: Tomer Israely, et al.
Published: (2014-01-01)

Synthetic Human TLR9-LRR11 Peptide Attenuates TLR9 Signaling by Binding to and thus Decreasing Internalization of CpG Oligodeoxynucleotides
by: Xichun Pan, et al.
Published: (2016-02-01)

Impaired innate immunity in Tlr4(-/-) mice but preserved CD8+ T cell responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-deficient mice.
by: Ana-Carolina Oliveira, et al.
Published: (2010-04-01)

Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation.
by: Amit Benbenishty, et al.
Published: (2019-03-01)

ASSOCIATION OF TLR2, TLR4, TLR9 GENE EXPRESSION RELATED TO INNATE IMMUNITY WITH IN VIVO ACUTE RESPIRATORY INFECTIONS CAUSED BY KLEBSIELLA PNEUMONIAE
by: E. V. Budanova, et al.
Published: (2018-06-01)

pDC Activation by TLR7/8 Ligand CL097 Compared to TLR7 Ligand IMQ or TLR9 Ligand CpG
by: Jing Wu, et al.
Published: (2019-01-01)

Differential use of TLR2 and TLR9 in the regulation of immune responses during the infection with Trypanosoma cruzi.
by: Humberto D Gravina, et al.
Published: (2013-01-01)

TLR4 and TLR9 Polymorphisms Effect on Inflammatory Response in End-Stage Renal Disease Patients
by: M. Santos-Martins, et al.
Published: (2014-09-01)

IMPACT OF SEVOFLURANE AND DESFLURANE ON THE DEVELOPMENT OF POST-PERFUSION CARDIAC FAILURE IN MYOCARDIAL REVASCULIZATION SURGERY WITH CARDIOPULMONARY BYPASS
by: Yu. S. Polushin, et al.
Published: (2018-01-01)

Relationship between Sevoflurane Plasma Concentration, Clinical Variables and Bispectral Index Values during Cardiopulmonary Bypass.
by: Rainer Nitzschke, et al.
Published: (2015-01-01)

Role of Mal/TIRAP in TLR2- and TLR4-, but not TLR5-Induced Corneal Inflammation
by: Williams, Susan R.
Published: (2010)