Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10

Background: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009...

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Main Authors: A Balouty Dehkordy, A Rafiei, SM Alavi, SM Latifi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2010-12-01
Series:Iranian Journal of Parasitology
Subjects:
Online Access:http://journals.tums.ac.ir/upload_files/pdf/17283.pdf
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spelling doaj-2b7d1c57b612411b81572ce73d4b287f2021-03-02T10:34:22ZengTehran University of Medical SciencesIranian Journal of Parasitology1735-70202008-238X2010-12-0154447Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10A Balouty DehkordyA RafieiSM AlaviSM LatifiBackground: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009-2010.Methods: Fecal samples from 176 immunocompromised patients were collected and Cryptosporid­ium coproantigen test was performed using ELISA method (DRG kit, Germany). A questionnaire was completed for each case and the results were analyzed using descriptive and Chi-Square tests, by SPSS statistical software (15th version).Results: Our study indicated 5.1% Cryptosporidium infection prevalence in the immunocompro­mised participated population. Furthermore, 4.2 %, 4%, 4.5 % and 9.1% infection rates were identi­fied in children suffered from hematopoietic malignancy, adult cancer patients, renal trans­plant recipients, and HIV+ cases, respectively. There was not significant correlation between the infection and age and gender (P>0.05). Infection was most frequent among HIV+ patients.Conclusion: The present study confirmed the high prevalence of Cryptosporidium antigen in fe­cal samples of immunocompromised patients in the region. As no chemotherapeutic agents have yet proven, especially in immunosuppressed patients, therefore our results highlight the impor­tance of preventive intervention in these groups.http://journals.tums.ac.ir/upload_files/pdf/17283.pdfCryptosporidiumCoproantigenImmunocompromised PatientsELISAHumanIran
collection DOAJ
language English
format Article
sources DOAJ
author A Balouty Dehkordy
A Rafiei
SM Alavi
SM Latifi
spellingShingle A Balouty Dehkordy
A Rafiei
SM Alavi
SM Latifi
Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
Iranian Journal of Parasitology
Cryptosporidium
Coproantigen
Immunocompromised Patients
ELISA
Human
Iran
author_facet A Balouty Dehkordy
A Rafiei
SM Alavi
SM Latifi
author_sort A Balouty Dehkordy
title Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
title_short Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
title_full Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
title_fullStr Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
title_full_unstemmed Prevalence of Cryptosporidium Infection in Immunocompromised Pa-tients, In South-West of Iran, 2009-10
title_sort prevalence of cryptosporidium infection in immunocompromised pa-tients, in south-west of iran, 2009-10
publisher Tehran University of Medical Sciences
series Iranian Journal of Parasitology
issn 1735-7020
2008-238X
publishDate 2010-12-01
description Background: Cryptosporidium is a protozoan parasite with worldwide distribution. The aim of this study was to estimate the prevalence of Cryptosporidium infection by antigen detection in faeces among immunocompromised patients referred to educational hospitals of Ahvaz City, South-West of Iran, 2009-2010.Methods: Fecal samples from 176 immunocompromised patients were collected and Cryptosporid­ium coproantigen test was performed using ELISA method (DRG kit, Germany). A questionnaire was completed for each case and the results were analyzed using descriptive and Chi-Square tests, by SPSS statistical software (15th version).Results: Our study indicated 5.1% Cryptosporidium infection prevalence in the immunocompro­mised participated population. Furthermore, 4.2 %, 4%, 4.5 % and 9.1% infection rates were identi­fied in children suffered from hematopoietic malignancy, adult cancer patients, renal trans­plant recipients, and HIV+ cases, respectively. There was not significant correlation between the infection and age and gender (P>0.05). Infection was most frequent among HIV+ patients.Conclusion: The present study confirmed the high prevalence of Cryptosporidium antigen in fe­cal samples of immunocompromised patients in the region. As no chemotherapeutic agents have yet proven, especially in immunosuppressed patients, therefore our results highlight the impor­tance of preventive intervention in these groups.
topic Cryptosporidium
Coproantigen
Immunocompromised Patients
ELISA
Human
Iran
url http://journals.tums.ac.ir/upload_files/pdf/17283.pdf
work_keys_str_mv AT abaloutydehkordy prevalenceofcryptosporidiuminfectioninimmunocompromisedpatientsinsouthwestofiran200910
AT arafiei prevalenceofcryptosporidiuminfectioninimmunocompromisedpatientsinsouthwestofiran200910
AT smalavi prevalenceofcryptosporidiuminfectioninimmunocompromisedpatientsinsouthwestofiran200910
AT smlatifi prevalenceofcryptosporidiuminfectioninimmunocompromisedpatientsinsouthwestofiran200910
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