A mitotic recombination map proximal to the <it>APC </it>locus on chromosome 5q and assessment of influences on colorectal cancer risk

A mitotic recombination map proximal to the <it>APC </it>locus on chromosome 5q and assessment of influences on colorectal cancer risk

<p>Abstract</p> <p>Background</p> <p>Mitotic recombination is important for inactivating tumour suppressor genes by copy-neutral loss of heterozygosity (LOH). Although meiotic recombination maps are plentiful, little is known about mitotic recombination. The <it>A...

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Bibliographic Details
Main Authors: Clark Susan, Guenther Thomas, Spain Sarah, Jones Angela, Rowan Andrew, Harvey John J, Schaschl Helmut, Teixeira Ana, Winter Eitan, Ranta Susanna, Howarth Kimberley, Stewart Aengus, Silver Andrew, Tomlinson Ian
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/54

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