Perspectives on Hypoxia Signaling in Tumor Stroma

Perspectives on Hypoxia Signaling in Tumor Stroma

Hypoxia is a well-known characteristic of solid tumors that contributes to tumor progression and metastasis. Oxygen deprivation due to high demand of proliferating cancer cells and standard of care therapies induce hypoxia. Hypoxia signaling, mainly mediated by the hypoxia-inducible transcription fa...

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Bibliographic Details
Main Authors: Yuqing Zhang, Morgan Coleman, Rolf A. Brekken
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
hypoxia
HIF
tumor stroma
immune microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/12/3070

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