A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

<p>Abstract</p> <p>Background</p> <p>Targeting Signal Transducer and Activator of Transcription 3 (STAT3) signaling is an attractive therapeutic approach for most types of human cancers with constitutively activated STAT3. A novel small molecular STAT3 inhibitor, FLLL32...

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Bibliographic Details
Main Authors: Lin Li, Deangelis Stephanie, Foust Elizabeth, Fuchs James, Li Chenglong, Li Pui-Kai, Schwartz Eric B, Lesinski Gregory B, Benson Don, Lü Jiagao, Hoyt Dale, Lin Jiayuh
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/217