MDM2 is a novel E3 ligase for HIV-1 Vif

MDM2 is a novel E3 ligase for HIV-1 Vif

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<p>Abstract</p> <p>The human immunodeficiency virus type 1 (HIV-1) Vif plays a crucial role in the viral life cycle by antagonizing a host restriction factor APOBEC3G (A3G). Vif interacts with A3G and induces its polyubiquitination and subsequent degradation via the formation of ac...

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Bibliographic Details
Main Authors:	Tomonaga Mitsunori, Sato Toshihiro, Kondoh Hiroshi, Iwai Kazuhiro, Matsui Masashi, Io Katsuhiro, Itoh Katsuhiko, Higashitsuji Hiroaki, Shirakawa Kotaro, Takaori-Kondo Akifumi, Izumi Taisuke, Ikeda Satoru, Akari Hirofumi, Koyanagi Yoshio, Fujita Jun, Uchiyama Takashi
Format:	Article
Language:	English
Published:	BMC 2009-01-01
Series:	Retrovirology
Online Access:	http://www.retrovirology.com/content/6/1/1

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