Oral Treatment with Extract of Agaricus blazei Murill Enhanced Th1 Response through Intestinal Epithelial Cells and Suppressed OVA-Sensitized Allergy in Mice

Oral Treatment with Extract of Agaricus blazei Murill Enhanced Th1 Response through Intestinal Epithelial Cells and Suppressed OVA-Sensitized Allergy in Mice

To clarify the mechanism of the antiallergic activity of Agaricus blazei Murill extract (ABME), the present paper used an in vivo allergy model and an in vitro intestinal gut model. During OVA sensitization, the serum IgE levels decreased significantly in ABME group. Interleukin (IL)-4 and -5 produc...

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Bibliographic Details
Main Authors:	Go Bouike, Yosuke Nishitani, Hideyuki Shiomi, Masaru Yoshida, Takeshi Azuma, Takashi Hashimoto, Kazuki Kanazawa, Masashi Mizuno
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Evidence-Based Complementary and Alternative Medicine
Online Access:	http://dx.doi.org/10.1155/2011/532180

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