The emerging role of KDM5A in human cancer

The emerging role of KDM5A in human cancer

Abstract Histone methylation is a key posttranslational modification of chromatin, and its dysregulation affects a wide array of nuclear activities including the maintenance of genome integrity, transcriptional regulation, and epigenetic inheritance. Variations in the pattern of histone methylation...

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Bibliographic Details
Main Authors: Guan-Jun Yang, Ming-Hui Zhu, Xin-Jiang Lu, Yan-Jun Liu, Jian-Fei Lu, Chung-Hang Leung, Dik-Lung Ma, Jiong Chen
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Hematology & Oncology
Subjects:
KDM5A
Cancer
Jumonji C domain
Histone methylation
Drug resistance
Targeted therapy
Online Access:https://doi.org/10.1186/s13045-021-01041-1

Internet

https://doi.org/10.1186/s13045-021-01041-1

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