Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia

Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia

Weiyan Cheng,1,2,* Suhua Wang,1,2,* Zhiheng Yang,1,2 Xin Tian,1,2 Yongzhou Hu31Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, People’s Republic of China; 2Henan Key Laboratory of Precision Clinical Pharmacy, The First Affiliated Hospital of...

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Bibliographic Details
Main Authors: Cheng W, Wang S, Yang Z, Tian X, Hu Y
Format: Article
Language:English
Published: Dove Medical Press 2019-08-01
Series:Drug Design, Development and Therapy
Subjects:
EGFR inhibitor
hypoxia
tumor
4-anilinoquinazoline
2-nitroimidazole
Online Access:https://www.dovepress.com/design-synthesis-and-biological-study-of-4-2-nitroimidazole-1h-alkylox-peer-reviewed-article-DDDT

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https://www.dovepress.com/design-synthesis-and-biological-study-of-4-2-nitroimidazole-1h-alkylox-peer-reviewed-article-DDDT

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