Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome
The human skin has a highly developed extracellular matrix (ECM) that is vital for proper skin functioning, its 3D architecture playing a pivotal role in support and guidance of resident and invading cells. To establish relevant in vitro models mimicking the complex design observed in vivo, scaffold...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
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Series: | Matrix Biology Plus |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590028521000107 |