Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone

Torsade de Pointes and Persistent QTc Prolongation after Intravenous Amiodarone

We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to...

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Bibliographic Details
Main Authors: Anna P. Kotsia, Georgios Dimitriadis, Giannis G. Baltogiannis, Theofilos M. Kolettis
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/673019
Description
Summary:We report a case of torsade de pointes after intravenous amiodarone and concurrent hypokalemia. Despite treatment cessation and correction of electrolyte abnormalities, excessive QTc prolongation was noted, which persisted for 14 days. This prolonged course for QTc normalization may be attributed to the high rate of amiodarone loading and concurrent electrolyte disturbances coupled with possible underlying individual variability in pharmacokinetics.
ISSN:1687-9627
1687-9635

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