Complex DNA knots detected with a nanopore sensor

Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.

Bibliographic Details
Main Authors: Rajesh Kumar Sharma, Ishita Agrawal, Liang Dai, Patrick S. Doyle, Slaven Garaj
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12358-4
Description
Summary:Nanopore microscopy is capable of detecting knots in DNA polymers, a common structural feature. Here the authors show nanopore sensors can map the equilibrium structure of these knots between tight and loose states.
ISSN:2041-1723