Targeted delivery of doxorubicin by CSA-binding nanoparticles for choriocarcinoma treatment

Targeted delivery of doxorubicin by CSA-binding nanoparticles for choriocarcinoma treatment

Gestational trophoblastic neoplasia (GTN) can result from the over-proliferation of trophoblasts. Treatment of choriocarcinoma, the most aggressive GTN, currently requires high doses of systemic chemotherapeutic agents, which result in indiscriminate drug distribution and severe toxicity. To overcom...

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Bibliographic Details
Main Authors: Baozhen Zhang, Guogang Cheng, Mingbin Zheng, Jinyu Han, Baobei Wang, Mengxia Li, Jie Chen, Tianxia Xiao, Jian Zhang, Lintao Cai, Shoujun Li, Xiujun Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
chondroitin sulfate a
csa-bind peptide
nanoparticles
drug delivery
tumor targeting
choriocarcinoma
Online Access:http://dx.doi.org/10.1080/10717544.2018.1435750

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