NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression

NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression

Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) is a long and inefficient process. A thorough understanding of the molecular mechanisms underlying reprogramming is paramount for efficient generation and safe application of iPSCs in medicine. While intensive efforts have been de...

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Bibliographic Details
Main Authors: Francesco Faiola, Nuoya Yin, Miguel Fidalgo, Xin Huang, Arven Saunders, Junjun Ding, Diana Guallar, Baoyen Dang, Jianlong Wang
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Stem Cell Reports
Subjects:
NAC1/BTBD14B
iPSC
E-cadherin
Zeb1
miR-200
Nanog
pluripotency
reprogramming
mesenchymal-to-epithelial transition
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117303119

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