Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways
Arca subcrenata is documented in the literature of marine Traditional Chinese Medicine. Polypeptide fraction from A. subcrenata, coded as P2, was demonstrated to possess significant antitumor activity in our previous study. However, the underlying mechanism remains undefined. The present study was c...
Main Authors: | Xianjing Hu, Zhang Zhang, Ting Liu, Liyan Song, Jianhua Zhu, Zhongyi Guo, Jinghua Cai, Rongmin Yu |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
|
Series: | Evidence-Based Complementary and Alternative Medicine |
Online Access: | http://dx.doi.org/10.1155/2015/930249 |
Similar Items
-
The Inhibitory Effect of a Novel Polypeptide Fraction from Arca subcrenata on Cancer-Related Inflammation in Human Cervical Cancer HeLa Cells
by: Yu Wu, et al.
Published: (2014-01-01) -
Antitumor Effect of a Polypeptide Fraction from Arca subcrenata in Vitro and in Vivo
by: Rongmin Yu, et al.
Published: (2012-12-01) -
A New Antiproliferative and Antioxidant Peptide Isolated from Arca subcrenata
by: Qin Zheng, et al.
Published: (2013-05-01) -
Antioxidant Activities of Hydrolysates of Arca Subcrenata Prepared with Three Proteases
by: Liyan Song, et al.
Published: (2008-11-01) -
Purification, Characterization and in vitro Anti-Tumor Activity of Proteins from Arca subcrenata Lischke
by: Yu Zhao, et al.
Published: (2008-07-01)