Polyphenol-rich Boswellia serrata gum prevents cognitive impairment and insulin resistance of diabetic rats through inhibition of GSK3β activity, oxidative stress and pro-inflammatory cytokines

Polyphenol-rich Boswellia serrata gum prevents cognitive impairment and insulin resistance of diabetic rats through inhibition of GSK3β activity, oxidative stress and pro-inflammatory cytokines

Type 2 diabetes (T2D) is associated with accelerated cognitive decline. To date, there is no T2D-specific treatment to prevent or ameliorate cognitive dysfunction. Boswellia serrate (BS) gum has been shown to possess multiple pharmacological actions including anti-inflammatory, anticancer and ant- a...

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Bibliographic Details
Main Authors: Adel A. Gomaa, Rania M. Makboul, Mohamed A. Al-Mokhtar, Mariam A. Nicola
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Alzheimer's disease-like alterations
Insulin resistance
Oxidative stress
Cytokines
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218360190

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