Understanding the structural details of APOBEC3-DNA interactions using graph-based representations

Human APOBEC3 (A3; apolipoprotein B mRNA editing catalytic polypeptide-like 3) is a family of seven enzymes involved in generating mutations in nascent reverse transcripts of many retroviruses, as well as the human genome in a range of cancer types. The structural details of the interaction between...

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Bibliographic Details
Main Authors: J.C.-F. Ng, F. Fraternali
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Current Research in Structural Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665928X20300143