Sindbis viral vector induced apoptosis requires translational inhibition and signaling through Mcl-1 and Bak

<p>Abstract</p> <p>Background</p> <p>Sindbis viral vectors are able to efficiently target and kill tumor cells <it>in vivo</it>, as shown using pancreatic and ovarian cancer models. Infection results in apoptosis both <it>in vitro </it>and <it...

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Bibliographic Details
Main Authors: Meruelo Daniel, Venticinque Lisa
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/37