Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

<p>Abstract</p> <p>Background</p> <p>The COP9/signalosome (CSN) is a highly conserved eight subunit complex that, by deneddylating cullins in cullin-based E3 ubiquitin ligases, regulates protein degradation. Although studied in model human cell lines such as HeLa, very...

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Bibliographic Details
Main Authors: Bunce Christopher M, Hayden Rachel E, Pearce Claire, Khanim Farhat L
Format: Article
Language:English
Published: BMC 2009-04-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/10/31

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