The Effects of Lycopene on the Methylation of the GSTP1 Promoter and Global Methylation in Prostatic Cancer Cell Lines PC3 and LNCaP

The Effects of Lycopene on the Methylation of the GSTP1 Promoter and Global Methylation in Prostatic Cancer Cell Lines PC3 and LNCaP

DNA (cytosine-5-) methylation silencing of GSTP1 function occurs in prostate adenocarcinoma (PCa). Previous studies have shown that there is an inverse relationship between dietary lycopene intake and the risk of PCa. However, it is unknown whether lycopene reactivates the tumor suppressor gene glut...

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Bibliographic Details
Main Authors:	Li-Juan Fu, Yu-Bin Ding, Lan-Xiang Wu, Chun-Jie Wen, Qiang Qu, Xue Zhang, Hong-Hao Zhou
Format:	Article
Language:	English
Published:	Hindawi Limited 2014-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2014/620165

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