The Effect of Intravenous Autologous Activated Platelet-Rich Plasma Therapy on “Profibrotic Cytokine” IL-1β Levels in Severe and Critical COVID-19 Patients: A Preliminary Study

The Effect of Intravenous Autologous Activated Platelet-Rich Plasma Therapy on “Profibrotic Cytokine” IL-1β Levels in Severe and Critical COVID-19 Patients: A Preliminary Study

Introduction. Elevated concentration of proinflammatory cytokines followed by hyperinflammation is one of the hallmarks of severe and critical COVID-19. In the short term, this may result in ARDS and lung injury; subsequently, this may cause pulmonary fibrosis—a disease with poor prognosis—in the lo...

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Main Authors: Karina Karina, Louis Martin Christoffel, Rita Novariani, Imam Rosadi, Iis Rosliana, Siti Rosidah, Siti Sobariah, Novy Fatkhurohman, Nurlaela Puspitaningrum, Yuli Hertati, Irsyah Afini, Difky Ernanda, Tias Widyastuti, A. D. Sulaeha, Alfida Zakiyah, Noor Aini, Grady Krisandi, Hubert Andrew
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2021/9427978

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