Matrix Stiffness Modulates Metabolic Interaction between Human Stromal and Breast Cancer Cells to Stimulate Epithelial Motility

Matrix Stiffness Modulates Metabolic Interaction between Human Stromal and Breast Cancer Cells to Stimulate Epithelial Motility

Breast tumors belong to the type of desmoplastic lesion in which a stiffer tissue structure is a determinant of breast cancer progression and constitutes a risk factor for breast cancer development. It has been proposed that cancer-associated stromal cells (responsible for this fibrotic phenomenon)...

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Bibliographic Details
Main Authors: Iván Ponce, Nelson Garrido, Nicolás Tobar, Francisco Melo, Patricio C. Smith, Jorge Martínez
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
stiffness
breast cancer
lactate
monocarboxylate transporters
Online Access:https://www.mdpi.com/2218-1989/11/7/432

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