Synthesis and characterization of tricarbonyl-Re/Tc(I) chelate probes targeting the G protein-coupled estrogen receptor GPER/GPR30.

The discovery of the G protein-coupled estrogen receptor GPER (also GPR30) and the resulting development of selective chemical probes have revealed new aspects of estrogen receptor biology. The potential clinical relevance of this receptor has been suggested from numerous studies that have identifie...

Full description

Bibliographic Details
Main Authors: Ritwik Burai, Chinnasamy Ramesh, Tapan K Nayak, Megan K Dennis, Bj K Bryant, Eric R Prossnitz, Jeffrey B Arterburn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3471960?pdf=render