Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library.

Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library.

Chikungunya virus (CHIKV) is a mosquito-borne arthrogenic alphavirus that causes acute febrile illness in humans accompanied by joint pains and in many cases, persistent arthralgia lasting weeks to years. The re-emergence of CHIKV has resulted in numerous outbreaks in the eastern hemisphere, and thr...

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Bibliographic Details
Main Authors: Deu John M Cruz, Rafaela M Bonotto, Rafael G B Gomes, Camila T da Silva, Juliana B Taniguchi, Joo Hwan No, Benoit Lombardot, Olivier Schwartz, Michael A E Hansen, Lucio H Freitas-Junior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3814572?pdf=render

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http://europepmc.org/articles/PMC3814572?pdf=render

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