Silencing of circRNA circ_0001666 Represses EMT in Pancreatic Cancer Through Upregulating miR-1251 and Downregulating SOX4

Silencing of circRNA circ_0001666 Represses EMT in Pancreatic Cancer Through Upregulating miR-1251 and Downregulating SOX4

BackgroundPancreatic cancer (PC) is an aggressive malignancy and has a poor prognosis. Although emerging research has revealed that circular RNAs (circRNAs) are crucial modulators that control tumor development and metastasis, their functional involvement in PC has not been well characterized. Here,...

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Bibliographic Details
Main Authors: Rundong Zhang, Wanli Zhu, Chenchao Ma, Kaixing Ai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
circ_0001666
circular RNA
circRNA
pancreatic cancer
microRNA-1251
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.684866/full

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